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Performing Resistance Exercise Prior to Aerobic Exercise Results in Higher Growth Hormone Levels during Exercise in Physically Active Individuals with Well‐Controlled Type 1 Diabetes

2013· article· en· W2581733411 on OpenAlexaffabout
Jane E. Yardley, Ronald J. Sigal, Bruce A. Perkins, Michael C. Riddell, Glen P. Kenny

Bibliographic record

VenueThe FASEB Journal · 2013
Typearticle
Languageen
FieldMedicine
TopicGrowth Hormone and Insulin-like Growth Factors
Canadian institutionsYork UniversityUniversity of TorontoUniversity of CalgaryUniversity of Ottawa
Fundersnot available
KeywordsAerobic exerciseMedicineLipolysisInternal medicineEndocrinologyTreadmillPhysical exerciseHypoglycemiaInsulin resistanceType 1 diabetesResistance trainingDiabetes mellitusType 2 diabetesGrowth hormoneHormoneAdipose tissue

Abstract

fetched live from OpenAlex

Background Performing resistance exercise before aerobic exercise (rather than the reverse) can protect against exercise‐induced hypoglycemia in physically active well‐controlled individuals with type 1 diabetes (T1D). Growth hormone (GH) is a potential mediator of this phenomenon as it promotes lipolysis, thereby sparing blood glucose. Purpose This research aimed to determine whether GH secretion is affected by the order in which resistance ( R ) and aerobic ( A ) exercise are performed in people with T1D. Methods On separate days, 6 physically active participants with T1D (HbA 1c 7.0±1.0%) either ran on a treadmill for 45‐min prior to performing 45‐min of weight lifting ( AR ) or performed the resistance exercise before running ( RA ). Results GH (mean±SE) rose only transiently in AR, but the rise was larger and more sustained in RA. Differences between sessions were statistically significant for the last 30‐min of exercise (mean at 60 minutes: AR = 2.86±1.03 vs RA = 5.86±1.91 μg/L; at 75 minutes: AR = 1.98±0.78 vs RA = 7.17±2.54 μg/L; at 90 minutes: AR = 1.98±0.82 vs RA = 6.67±2.51 μg/L. Conclusion GH patterns are consistent with this hormone being a mediator in the stabilization of blood glucose levels when aerobic exercise is performed subsequent to resistance exercise in habitually active individuals with T1D. Supported by the Canadian Diabetes Association and the Ottawa Hospital Research Institute.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.227
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes2
Has abstractyes

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