Gavage Feeding Practices in VLBW Infants: Physiological Aspects and Clinical Implications
Bibliographic record
Abstract
The goal of enteral nutrition in preterm infants is to adequately support growth without compromising the integrity of the immature gut. Gavage feeds given both by intermittent bolus and continuous infusion have been used in NICUs for years. There is no clear evidence that one method improves clinical outcome over the other, leading to practice variations that are often empirical and subject to clinician preference. This article reviews the physiological effects of the feeding method on gut perfusion, motility, energy expenditure, and interoceptive stress with special regard to anabolism and bioavailability of nutrients. Bolus feeding is followed by insulin surges, enhanced protein synthesis, and improved intestinal growth. Infusion feeding leads to a mature pattern of duodenal contractions and less energy expenditure but is associated with significant loss of key nutrients. An individualized approach based on physiological needs of preterm infants may improve feeding tolerance in this population.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".