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Record W2586542468 · doi:10.1093/pch/14.suppl_a.54aa

Reduced Daily Dosing of Cefazolin with Probenecid for the Outpatient Treatment of Cellulitis in Children

2009· article· en· W2586542468 on OpenAlexaff
GC Thompson, JD Kellner, FP Belanger

Bibliographic record

VenuePaediatrics & Child Health · 2009
Typearticle
Languageen
FieldMedicine
TopicAntibiotics Pharmacokinetics and Efficacy
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsProbenecidDosingCefazolinCellulitisMedicineIntensive care medicineAnesthesiaSurgeryPharmacologyAntibioticsMicrobiologyBiology

Abstract

fetched live from OpenAlex

independent of an ASD diagnosis.Children with ASD and ADHD represent a specific subtype of ASD, with identifiable characteristics.METHODS/ ANALySIS: A retrospective chart review was conducted.Information gathered included sex, age, IQ, communication profile, Autism Diagnostic Observation Schedule, Autism Diagnostic Interview, adaptive skills and Conners Parent Rating Scale subscale scores.Hierarchical linear models were used to estimate the effect of sex and diagnosis on raw Conners index scores, after controlling for age and adjusting for the correlation among individuals of the same family.An interaction between group and sex was introduced into the model in order to estimate within group gender effect and the effect of diagnosis within each gender.RESULTS: Data from 72 children diagnosed with autism were analyzed.Of these, 15 (20.8%) met the DSM-IV criteria for ADHD, with 2 (13.3%) meeting criteria for the hyperactive impulsive profile, 7 (46.7%) the inattentive profile and 6 (40%) meeting the criteria for the combined profile.When using a less conservative cutoff, an additional 39 (54%) children diagnosed with ASD demonstrated at least six symptoms of hyperactivity, impulsivity and or inattention.Only 18 (25%) children diagnosed with ASD displayed no symptoms of ADHD.Girls with ASD were more likely to be hyperactive and impulsive whilst unaffected sibling males were inattentive.SIGNIFICANCE: These data suggest that there are at least three different subtypes to describe the presentation of ADHD symptoms in children diagnosed with ASD.The three subtypes are the asymptomatic, sub clinical and a clinical group.This adds strength to the dimensional approach to classifying and interpreting symptoms in children diagnosed with autism.This challenges the present DSM-IV criteria which fail to recognize the coexistence of ADHD in ASD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.292
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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