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Record W2588201397 · doi:10.1093/ndt/gfw178.14

SP655ASSOCIATION OF ABDOMINAL CIRCUMFERENCE AND INFLAMMATION IN KIDNEY TRANSPLANT RECIPIENTS

2016· article· en· W2588201397 on OpenAlexaff
Kristóf Nagy, Ákos Újszászi, Ádám Remport, Csaba P. Kövesdy, István Mucsi, Miklos Z. Molnar, Zoltán Máthé

Bibliographic record

VenueNephrology Dialysis Transplantation · 2016
Typearticle
Languageen
FieldMedicine
TopicPotassium and Related Disorders
Canadian institutionsUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsMedicineKidney transplantCircumferenceInflammationInternal medicineKidneyKidney transplantationMathematics

Abstract

fetched live from OpenAlex

Introduction and Aims: Increased abdominal circumference is a marker of obesity and it is associated with increased mortality in renal transplant recipients. Recent findings suggest that increased visceral fat deposition is a modifier of inflammation. However, little is known about the relation of inflammation and abdominal circumference in kidney transplant recipients. Methods: We collected socio-demographic and clinical parameters, medical and transplant history, and laboratory data from 985 prevalent kidney transplant recipients enrolled in the Malnutrition-Inflammation in Transplant - Hungary Study (MINIT-HU study). Abdominal circumference and inflammatory markers were measured at baseline. Associations between inflammatory markers and abdominal circumference were examined in unadjusted and adjusted regression models. Results: Mean±SD age was 51±13 years, 57% were men and 21% were diabetics. Patients with abdominal circumference above the median had higher body mass index and were older (mean±SD: 23.9±3.6 vs. 30.1±3.9 kg/m², p<0.001; and 48±14 vs. 54±11 years, p<0.001). Furthermore patients with higher abdominal circumference had increased inflammatory parameters: median (InterQuartile Range) CRP(mg/L): 2.3 (3.9) vs. 4.1 (6.2), p<0.001; and IL6(pg/ml): 1.9 (2.2) vs. 2.3 (2.4), p<0.001. In multivariable adjusted linear regression models higher abdominal circumference showed significant linear associations with inflammatory markers (standardized regression coefficients (β) of abdominal circumference: for lnCRP: βabdominal circumference=0.29, p<0.001; and for lnIL-6: βabdominal circumference=0.09, p=0.018).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.446
Threshold uncertainty score0.312

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.233
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

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