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A national survey on the management of liver metastases from colorectal cancer (CRC): Comparison of perspectives and expectations among medical oncologists and hepatobiliary surgeons across Canada.

2016· article· en· W2591502620 on OpenAlexaffabout
Maria Yi Ho, Sean P. Cleary, Matthew Mazurek, Sunita Ghosh, Winson Y. Cheung

Bibliographic record

VenueJournal of Clinical Oncology · 2016
Typearticle
Languageen
FieldMedicine
TopicHepatocellular Carcinoma Treatment and Prognosis
Canadian institutionsUniversity of AlbertaBC Cancer AgencyPrincess Margaret Cancer CentreUniversity of TorontoUniversity Health NetworkMount Sinai Hospital
Fundersnot available
KeywordsMedicineColorectal cancerGeneral surgeryHepatectomyCancerResectionInternal medicineSurgery

Abstract

fetched live from OpenAlex

690 Background: To compare the perspectives of medical oncologists versus hepatobiliary surgeons in the management of liver metastases from CRC. Methods: Medical oncologists and hepatobiliary surgeons across Canada were surveyed to evaluate for criteria used to determine resectability of liver metastases from CRC and availability of multidisciplinary clinics. Results: Of 220 experts surveyed, 145 (66%) responded. 137 (95%) had received specialized training in oncology. Only 37 (26%) respondents reported access to both multi-disciplinary tumor boards and clinics. 109 (75%) reported lack of institutional criteria. Oncologists and surgeons disagreed with regard to absolute contraindications for resection of hepatic metastases. More oncologists reported a higher percentage of liver parenchyma involvement (70% vs. 45%), proximity to major vessels and poor performance status as contraindications compared to surgeons (p < 0.05). All physicians deemed CT as the preferred first-line imaging study for evaluating CRC liver metastases with significantly more surgeons indicating the need for MRI of the liver (p < 0.05). Oncologists and surgeons also showed high discordances with respect to both clinical and radiographic findings in terms of their influence on surgical decision regarding resection of liver metastases (Table). Conclusions: Medical Oncologists and surgeons have discordant criteria with respect to resection of hepatic metastases and the roles they play in the management of these complex patients. Uncertainties and discordances can lead to deficiencies in care, supporting the need for a standardized clinical preoperative risk scoring system for resection of liver metastases from CRC. [Table: see text]

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.157
Threshold uncertainty score0.316

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.239
GPT teacher head0.455
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes2
Has abstractyes

Explore more

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