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Record W2592924673 · doi:10.12691/jfnr-5-2-10

Clinical Evaluation of Blood Glucose Regulation and Safety of Cordyceps cicadae Mycelium

2017· article· en· W2592924673 on OpenAlexaff
Chin‐Chu Chen, Te-Chih Wong, Chen‐Ling Huang, Bo-Yi Jhou, Jui‐Hsia Hsu, Shu‐Hsing Yeh, Yueh‐Ting Tsai, Shwu‐Huey Yang

Bibliographic record

VenueJournal of food and nutrition research · 2017
Typearticle
Languageen
FieldMedicine
TopicFungal Biology and Applications
Canadian institutionsArtificial Intelligence in Medicine (Canada)
Fundersnot available
KeywordsMedicineMyceliumTraditional medicinePlaceboUrinalysisCordycepsIngredientAdverse effectInternal medicinePhysiologyUrineBiologyAlternative medicinePathology

Abstract

fetched live from OpenAlex

Cordyceps cicadae (C. cicadae) is one of the most valued traditional Chinese medicines and have been used for about 1600 years in China. It is edible and is used traditionally for vision improvement, renal protection, cancer treatment and regulation of blood cholesterol and blood glucose. The aim of this study was to evaluate the safety and to determine the effects of Cordyceps cicadae (C. cicadae) mycelium on hyperglycemic patients or type 2 diabetic patients by a single-blind, randomized, parallel-group, and placebo-controlled trial. In the treatment group, 22 subjects ingested a supplement containing freeze-dried C. cicadae mycelium powder (1050 mg/day) in hard capsule form, every day for 3 months. In the placebo group, 18 subjects ingested placebo capsules. Before supplementation, subjects completed a questionnaire to assess for personal data (age, medical history, medication record, physical activity). Subjects underwent blood pressure reading, anthropometric measurements, biochemical investigations, oral glucose tolerance test (OGTT) and urinalysis at baseline, the end of treatment period, and the end of follow-up period. Based on the results, freeze-dried C. cicadae mycelium powder could maintain blood glucose level in hyperglycemic patient or type 2 diabetic patients. Besides, no toxicity observed in kidney and liver. Results from the study do not raise concern with respect to possible use as a functional food ingredient. This study provides support for the use of C. cicadae fermentation product as a safe agent in functional food.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.729
Threshold uncertainty score0.168

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.173
GPT teacher head0.482
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2017
Admission routes1
Has abstractyes

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