Resolution of Acquired von Willebrand Disease Secondary to Hypertrophic Obstructive Cardiomyopathy Following Septal Myectomy.
Bibliographic record
Abstract
We report the case of a patient with hypertrophic obstructive cardiomyopathy, severe gastrointestinal bleeding and acquired von Willebrand syndrome. Pre-operative blood tests showed normal von Willebrand factor activity with decrease of high molecular weight multimers. Septal myectomy was performed in treatment of his hypertrophic disease. Follow-up blood tests indicated normal von Willebrand factor activity and high molecular weight multimers levels. Gastrointestinal bleeding has not recurred following surgery. In conclusion, septal myectomy resolves von Willebrand syndrome secondary to hypertrophic obstructive cardiomyopathy. von Willebrand factor Multimer testing can be used for the diagnosis of acquired von Willebrand syndrome which should be considered in patients who have gastrointestinal bleeding coinciding with hypertrophic obstructive cardiomyopathy.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.006 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".