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Record W2595976454 · doi:10.1098/rstb.2016.0085

What is a vector?

2017· review· en· W2595976454 on OpenAlexafffund
Anthony J. Wilson, Eric R. Morgan, Mark Booth, Rachel Norman, Sarah E. Perkins, Heidi C. Hauffe, Nicole Mideo, Janis Antonovics, Hamish McCallum, Andy Fenton

Bibliographic record

VenuePhilosophical Transactions of the Royal Society B Biological Sciences · 2017
Typereview
Languageen
FieldMedicine
TopicViral Infections and Vectors
Canadian institutionsUniversity of Toronto
FundersSeventh Framework ProgrammeNatural Environment Research CouncilNatural Sciences and Engineering Research Council of CanadaDirectorate for Biological SciencesBritish Ecological SocietySight Research UKUniversity of PennsylvaniaJames Hutton InstituteLondon School of Hygiene and Tropical MedicineProvincia Autonoma di TrentoNational Science FoundationNational Institute of General Medical SciencesEcological Society of AmericaBiotechnology and Biological Sciences Research CouncilPennsylvania State University
KeywordsPerspective (graphical)Vector (molecular biology)WildlifeBiologyTransmission (telecommunications)EcologyEvolutionary ecologyPopulationRange (aeronautics)Data scienceEvolutionary dynamicsEvolutionary biologyManagement scienceComputer scienceHost (biology)Artificial intelligenceSociologyEngineeringGenetics

Abstract

fetched live from OpenAlex

Many important and rapidly emerging pathogens of humans, livestock and wildlife are 'vector-borne'. However, the term 'vector' has been applied to diverse agents in a broad range of epidemiological systems. In this perspective, we briefly review some common definitions, identify the strengths and weaknesses of each and consider the functional differences between vectors and other hosts from a range of ecological, evolutionary and public health perspectives. We then consider how the use of designations can afford insights into our understanding of epidemiological and evolutionary processes that are not otherwise apparent. We conclude that from a medical and veterinary perspective, a combination of the 'haematophagous arthropod' and 'mobility' definitions is most useful because it offers important insights into contact structure and control and emphasizes the opportunities for pathogen shifts among taxonomically similar species with similar feeding modes and internal environments. From a population dynamics and evolutionary perspective, we suggest that a combination of the 'micropredator' and 'sequential' definition is most appropriate because it captures the key aspects of transmission biology and fitness consequences for the pathogen and vector itself. However, we explicitly recognize that the value of a definition always depends on the research question under study.This article is part of the themed issue 'Opening the black box: re-examining the ecology and evolution of parasite transmission'.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.993
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.004
Bibliometrics0.0000.001
Science and technology studies0.0010.003
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.275
GPT teacher head0.419
Teacher spread0.144 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations99
Published2017
Admission routes2
Has abstractyes

Explore more

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