INVOLVEMENT OF THE PROSTATE BY CHRONIC LYMPHOCYTIC LYMPHOMA, CLINICAL AND PATHOLOGICAL CHARACTERIZATION
Bibliographic record
Abstract
Introduction: Few reports have described the involvement of the prostate by hematolymphoid infiltrate; the usual presentation is that of benign prostatic hyperplasia, because of the rarity of the condition; there is no specific diagnostic or treatment paradigm. We set out to study the clinicopathological features for this occurrence. Material and Method: This is a retrospective review to describe the clinical and pathological characters of secondary involvement of the prostate by chronic lymphocytic leukemia/lymphoma. Cohort included male patients above the age of 40 years who were diagnosed to have CLL with secondary infiltration of the prostate gland.Results: Among 1512 pathologies reviewed; nine patients were found to have involvement of the prostate gland by CLL. The discovery of the prostate involvement was proved either by pathology examination of prostate chips obtained by Tran Urethral Resection of the prostate or Tranrectal Ultrasound guided prostate biopsy. The average age 57.6 years, prostate specific antigen 2.52 ng/ml AUA-score 23/35, abnormal Digital Rectal Examination 2/9, prostate volume 64 gm. Cohort was contrasted with our institutional prostate diseases database.Conclusion: Prostate gland might be an overlooked site of Chronic Lymphocytic leukemia infiltrate; patients usually present with severe obstructive symptoms and/or abnormal PSA/Digital Rectal Examination. Urologists and pathologists and should be oriented to the mode of presentation, diagnostic and treatment approaches of this population of patients.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".