Influence of Isometric Exercise Training on Quadriceps Muscle Architecture and Strength in Obese Subjects with Knee Osteoarthritis
Bibliographic record
Abstract
Obese individuals have reduced quadriceps muscle strength relative to body mass that may increase the rate of \nprogression of knee osteoarthritis (OA). The purpose of this study was to evaluate the effects of isometric exercise \ntraining on quadriceps muscle architecture and strength in obese subjects with knee osteoarthritis. Methods: Fortyfour \nobese male subjects aged 40–65 years diagnosed with knee osteoarthritis were randomly assigned into group A \n(n=32) and group B (n=12). Group A subjects performed a 12-week isometric exercise program. Group B subjects \ndid not participate in any exercise program and maintained their ordinary activities for the same period. Both groups \nreceived the same conventional physical therapy program including hot packs and therapeutic ultrasonic. Muscle \nthickness, pennation angles and fascicle length of the vastus lateralis (VL) muscle of the affected knee were measured \nat rest by B-mode ultrasonography. Maximal voluntary isometric knee extension torque (MVIC) of the affected \nknee was measured using an isokinetic dynamometer. Knee pain and function were evaluated using visual analogue \npain scale (VAS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC). All variables were \nevaluated before and the end of the intervention period for both groups. Results: at the end of the program, group A \nsubjects showed significant improvements compared with group B subjects regarding MVIC and muscle architecture \nparameters (p<0.05). Also, there was significant improvement in post-test VAS and WOMAC scores in group A \nsubjects compared to group B subjects (p<0.05). Conclusion: A 12-week quadriceps isometric training program \nimproves knee pain and quadriceps muscle strength and architecture in obese subjects with knee OA. These results \nindicate that isometric training should be regarded as a proper exercise intervention for obese patients with knee OA.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".