Heterotrophic Ossification of Intercostal Muscle Flap Causing Refractory Esophageal Stricture
Bibliographic record
Abstract
CASE REPORT A 78-year-old man presented with a history of progressive solid food dysphagia for a few weeks. His history was notable for a recent diagnosis of gastroesophageal junction adenocarcinoma that was treated with Ivor-Lewis esophagectomy, with esophagogastric anastomosis and intercostal muscle flap (IMF) placement for leak and fistula management. Upper endoscopy showed stenosis of the esophageogastric anastamosis precluding the passage of a diagnostic gastroscope. There was no evidence of tumor recurrence. Balloon dilation was performed using a through-the-scope dilating balloon. The patient underwent multiple dilatations over the next 2 months (every 2 weeks), up to a diameter of 16.5 mm. However, the patient's symptoms recurred rapidly, with evidence of restenosis seen on endoscopy (Figure 1). Computed tomography (CT) showed extrinsic compression and narrowing of the esophageogastric anastomosis caused by heterotrophic ossification of the pedicled IMF (Figure 2). A fully covered esophageal stent was inserted to manage his refractory esophageal stricture. The stent was removed after 6 weeks, followed by rapid recurrence of his symptoms. The patient opted for nonoperative management with serial dilations.Figure 1.: Recurrence of the stricture with evidence of ulceration after dilation.Figure 2.: Chest CT showing (A) heterotrophic ossification of the intercostal muscle flap with resultant esophageal luminal narrowing, and (B) heterotrophic ossification of the intercostal muscle flap.IMFs were initially described by Shenstone for the use in thoracic surgery in 1936.1 IMFs are used during bronchial or esophageal surgeries to reinforce the anastomosis.2 They have been used in cases of esophageal perforation related to benign or malignant etiologies.3 Heterotrophic ossification of IMF is a process of abnormal bony formation of these flaps. This entity has been reported as an incidental finding on imaging. However, bronchial obstruction with resultant pain and infection is well described.4 The characteristic radiological features seen on CT imaging include discontinuous linear calcification that appears either as a single stripe or two parallel stripes with an average thickness of 4 mm (range, 1–8 mm). The radiological changes can be seen as soon as 1 week postoperatively.5 DISCLOSURES Author contributions: A. Alali wrote the manuscript. K. Waschke edited the manuscript and is the article guarantor. Financial disclosure: None to report. Informed consent was obtained for this case report. Received December 23, 2016; Accepted February 17, 2017
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".