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MICROFILTRATION OF BRILLIANT BLUE G DYE

2013· article· en· W2599828 on OpenAlex
Sri Krishna Mukkamala

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueRetina · 2013
Typearticle
Languageen
FieldEnvironmental Science
TopicWater Quality Monitoring and Analysis
Canadian institutionsColumbia College
Fundersnot available
KeywordsMicrofiltrationChemistryChromatographyMembrane

Abstract

fetched live from OpenAlex

In Brief Background: Brilliant Blue G (BBG) is a safe and effective dye used to highlight the internal limiting membrane during macular surgery. The authors proposed that the utilization of a 0.22-μm filter intraoperatively can reduce the risk of inoculating an eye with contaminated BBG. Methods: An in vitro model of contaminated BBG was prepared. Laboratory stock cultures of 7 organisms including, Staphyloccocus epidermidis, Streptococcus pneumoniae, Staphyloccocus aureus, Haemophilus influenza, Klebsiella pneumoniae, Fusarium species, and Candida albicans, were prepared in five 10-fold dilutions and injected into BBG vials. These mixtures were drawn with either a 5-μm filter, 0.22-μm, or without a filter and cultured on appropriate plates and growth conditions. Results: No culture plates that had inoculate drawn through a 0.22-μm filter showed evidence of growth. There was evidence of growth for all organisms when no filter was used. A 5 μm was insufficient to filter Fusarium species. Conclusion: Using a 0.22-μm filter in the intraoperative processing of BBG would likely reduce the risk of infectious endophthalmitis resulting from contaminated dye. Brilliant Blue G is a dye used to identify the internal limiting membrane during macular surgery and has been associated with a recent outbreak of Fusarium species endophthalmitis. We present in vitro evidence that the use of a 0.22-μm filter can reduce the risk of postoperative endophthalmitis associated with the use of Brilliant Blue G.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.089
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.205
Teacher spread0.197 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it