Bibliographic record
Abstract
Histopathology revealed an increased cell density of oligodendrocytes (3350.5 cells/mm 2 , compared to 1683.6 cells/mm 2 in adjacent normal-appearing white matter, p < 0.001). Myelination (luxol fast blue staining) was normal. Supernumerary cells were negative for IDH1R132H by immunohistochemistry, IDH1/ 2 wildtype by Sequenom, and negative for Ki-67, synaptophysin, and BRAF V600E. The overlying cortex was completely normal, with no gliosis, balloon cell, neuronal dysmorophology or calcification. The original neuropathologic diagnosis was oligodendroglial hamartoma, although a more descriptive diagnosis of focal oligodendroglial hyperplasia is preferred. The patient continues to have 1-2 nocturnal partial (focal with dyscognitive features) seizures per month, but has had no convulsive seizure since her surgery (4.5 year follow-up). Oligodendroglial hyperplasia is a poorly characterized subtype of microdysgenesis, and a rare cause of medically refractory epilepsy. Histologically, it is important that it is differentiated from oligodendroglioma. Because of the paucity of published cases, the clinical impact of surgical resection of oligodendroglial hyperplasia found within the seizure onset zone is uncertain.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.009 | 0.005 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.003 |
| Science and technology studies | 0.003 | 0.017 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.003 | 0.000 |
| Research integrity | 0.001 | 0.004 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".