MétaCan
Menu
Back to cohort
Record W2608430944 · doi:10.1093/sleepj/zsx050.933

0934 EVALUATING THE EFFECTS OF GENERAL ANESTHESIA ON SLEEP IN CHILDREN UNDERGOING ELECTIVE SURGERY

2017· article· en· W2608430944 on OpenAlexaff
Sarah Selvadurai, Jason T. Maynes, Conor Mc Donnell, Sharon L. Cushing, Evan J. Propst, Armando J. Lorenzo, Lisa J. Meltzer, Andrew Lim, Richard L. Horner, Indra Narang

Bibliographic record

VenueSLEEP · 2017
Typearticle
Languageen
FieldNeuroscience
TopicAnesthesia and Neurotoxicity Research
Canadian institutionsHealth Sciences CentreSunnybrook Health Science CentreHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsActigraphyMedicineSleep onset latencyAnesthesiaAnestheticSleep (system call)SevofluraneSleep onsetSleep disorderPhysical therapyInsomniaPsychiatry

Abstract

fetched live from OpenAlex

Sleep disturbance during early childhood can lead to cognitive impairment, behavioural disorders and emotional dysregulation. There is increasing interest on the factors that may contribute to impaired sleep following surgery. The impact of general anesthesia on sleep has become of emerging interest. The objective of this study is to identify potential effects of a general anesthetic on sleep. This is a prospective, observational study with children, aged 18 months to 8 years, undergoing general anesthesia for elective surgery. Subjects underwent actigraphy sleep monitoring for 14 days: 7 consecutive days prior to and following the surgery. Data regarding baseline behaviour patterns were collected using standardized behavioural assessments. One and three months after surgery, the actigraph was worn again for 7 days with completion of behavioural assessments. Eighteen patients (mean age 4.7 years, 78% male) underwent surgery. All patients received sevoflurane as the inhaled anesthetic agent. The median anesthetic duration was 111 minutes. Between baseline and 7-day postoperative period, actigraphy measures were not significantly different (sleep efficiency: p=0.67, total sleep time: p=0.99, wake after sleep onset: p=0.16, sleep onset latency: p=0.29). Among the 18 patients, 7 patients completed both the 1- and 3-month follow-up, where no significant differences were found in actigraphy measures across all time points. Additionally, no significant differences in mean scores were found for overall internalizing behaviour, (F(1.24, 7.43)=0.28, p=0.66), externalizing behaviour (F(1.23, 7.35)=0.28, p=0.67) and executive functioning (F(1.02, 4.08)=0.28, p=0.83). In this study, general anesthesia did not cause sleep disturbance or negative behaviour changes in children. These findings are reassuring to both physicians and parents. N/A

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.024
Threshold uncertainty score0.522

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.337
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

Explore more

Same venueSLEEPSame topicAnesthesia and Neurotoxicity ResearchFrench-language works237,207