0252 EXPERIMENTAL CUMULATIVE SLEEP RESTRICTION IMPAIRS WORKING MEMORY BUT NOT DECISION MAKING
Bibliographic record
Abstract
Eighteen percent of young adults are sleep deprived. Sleep deprivation leads to significant neurobehavioral impairments and compromises job and academic performance and driving safety. Data is scarce and contradictory regarding the impact of cumulative sleep deprivation on neurobehavioural functoning (NBF). The objective of this study was to assess the impact of cumulative sleep restriction on the NBF of young adults. Participants: Sixty-five healthy participants (ages 18–34).Design: A double-blind, placebo controlled, randomized trial. Participants were randomized into experimental and placebo conditions. Each participant completed a period of baseline protocol and an experimental period. The experimental period lasted 6 nights and had 2 conditions: 1) sleep restriction condition -participants were asked to restrict their sleep by one hour per night 2) placebo condition- participants were asked to use a lamp which had no clinical effects for 30 minutes during day time. NBF was assessed at baseline (Day 1) and following sleep manipulation (Day 12).Measures: Sleep duration was assessed using actigraphy, an accelerometer that measures sleep objectively based on movement. NBF was measured using the Cambridge Neuropsychological Test Automated Battery Spatial Span task and the Cambridge Gambling Task for working memory and decision-making, respectively. Poorer performance on spatial span task was found in the experimental condition compared to the placebo condition, controlling for baseline spatial span length, sex, age, sleep efficiency during experimental week, baseline sleep duration, and chronotype, (F(1,49)=5.18, p < 0.05). No significant effects for sleep restriction were found on decision making measures when comparing the experimental condition to the placebo condition. Young adults’ performance on spatial working memory task deteriorated following cumulative sleep deprivation whereas their performance on decision making task was not affected. The present study indicates that sleep deprivation has a differential impact on the NBF of young adults. Canadian Institutes for Health Research (Grant #275268) and the Fonds de Recherche Société et Culture (Grant #2013-OU-171270). Jose Arturo Santisteban received funding from the Mexican National Council for Science and Technology (CONACYT).
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.007 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".