1098 IMPROVEMENTS IN SUBJECTIVE SLEEP AND DEPRESSION ALONG THE COURSE OF ADJUNCTIVE PHOTOTHERAPY
Bibliographic record
Abstract
Depression is often associated with disrupted sleep. Sleep onset difficulties and sleep quality have been suspected to play an important role in the pathogenesis of depression. Phototherapy has the potential to restore sleep dysfunctions, which in turn may alleviate mood. This study examined the relationship between changes in sleep and depressive symptoms alongside adjunctive phototherapy. Twenty-two young individuals with depression (21.3 ± 5.2 years old; 76% female) were recruited from early-intervention mental health services in Sydney and Ottawa. Phototherapy was self-administered with green-blue light-emitting glasses for 60 minutes upon awakening for two weeks as an adjunct to standard clinical care. Prior to starting phototherapy (baseline), participants completed the Leeds Sleep Evaluation Questionnaire (LSEQ) and the Beck Depression Inventory-II (BDI-II). Following the two weeks of phototherapy, participants were asked to fill out the LSEQ and BDI-II once again (follow-up). After two weeks of adjunctive phototherapy, there was a marked reduction in depressive symptoms severity for 28% of participants, as defined by a shift to a lower depression severity category on the BDI-II. Overall, the ‘Getting To Sleep’ index of the LSEQ significantly improved from baseline to follow-up (t(20) = -2.192, p = .040). Additionally, improvements on the ‘Getting To Sleep’ (r = -.601, p = .004) and ‘Quality Of Sleep’ (r = -.511, p = .018) indexes both positively correlated with the improvement of depression severity. No significant correlations between the changes in BDI-II and changes in any other LSEQ subscales were found. These preliminary findings indicate that the antidepressant effects of bright light are associated with the degree of sleep improvement. Larger placebo-controlled trials are still required to a have a better understanding of the potential role of sleep restoration for mood enhancement following phototherapy. This work was partially funded by the Centre for Integrated Research and Understanding of Sleep (CIRUS), the Fonds de recherche du Québec - Santé (FRQS), and the Canadian Institutes of Health Research (CIHR).
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".