Platypnea Orthodeoxia Syndrome in a Patient With Pulmonary Arterial Hypertension
Bibliographic record
Abstract
Platypnea orthodeoxia syndrome (POS) is a rare syndrome traditionally defined as dyspnea or hypoxemia observed when changing from a recumbent to an upright or seated position. A patent foramen ovale (PFO) is often part of the underlying pathophysiology. Here, a 70-year-old woman with known PFO presented with new symptoms of a POS. A pulmonary arterial hypertension (PAH), treated with ambrisentan for years, was also known. In order to clarify the etiology of the new hemodynamic state, we performed a transesophageal echocardiography (TEE) in an upright position, which excluded a PFO-related cause of symptoms. A further investigation showed a chronic obstructive pulmonary disease, the treatment of which relieved of symptoms. This is the first described case of POS in patient with PAH. Although PFO is a common cause of POS and a PFO closure is often advised, careful differential diagnosis should be kept in mind. J Med Cases. 2017;8(6):187-190 doi: https://doi.org/10.14740/jmc2840e
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".