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Abstract P187: Assessing Gender Bias in the Treatment of Cardiovascular Disease in Canada

2011· article· en· W2621704414 on OpenAlexaffabout
Emily L. Eaton, Patrick S. Parfrey, David C. Mendelssohn, Phil McFarlane, Fernando Camacho, Bryan M. Curtis

Bibliographic record

VenueCirculation Cardiovascular Quality and Outcomes · 2011
Typearticle
Languageen
FieldMedicine
TopicSex and Gender in Healthcare
Canadian institutionsUniversity of TorontoMemorial University of Newfoundland
Fundersnot available
KeywordsMedicineDialysisRenal replacement therapyRetrospective cohort studyEmergency medicineCause of deathDiseaseIntensive care medicineInternal medicine

Abstract

fetched live from OpenAlex

The objective of this study was to determine the presence of gender bias in the treatment of CVD in Canada. Gender bias has been explored extensively in the treatment of CVD, particularly AMI. Previous research is inconsistent in suggesting that women who suffer an AMI are treated less optimally than men. To date, gender bias has not been well addressed in other CVD's, specifically CVA, CABG, or RRT. In an attempt to get a clearer grasp of the problem, CAP was also studied and served as a control. Retrospective chart reviews for all AMI's, CVA's, CABG's, and CAP's in 1995/6, 1998/9, and 2000/1 in two locations of Newfoundland (St. John's and central) were reviewed. Outcomes were analyzed for differences between men and women. Adjusting for baseline differences, regression models were used to assess the following: AMI - time to thrombolytics, admission to CCU, death, discharge beta blockers, ACE/ARB, anti-lipids, ASA; CVA - LOS, transfer to and time to rehabilitation center, death; CABG - time to CABG; CAP - appropriateness of antibiotics (AB), death. RRT was analyzed from the results of the STARRT (Study To Assess Renal Replacement Therapy) study, a Canadian multicentre retrospective chart review of incident dialysis patients followed for six months. Outcomes were explored for differences in care between men and women. Optimal care was based on 1) length of pre-dialysis care; 2) modality choice; 3) access; 4) laboratory parameters at dialysis start; 5) clinical outcomes. Women who had suffered an AMI had a significantly longer time to thrombolytics and were less likely to be admitted to the CCU but did not differ significantly from men in other modes of treatment. Women who were RRT patients began dialysis at a lower eGFR level after receiving less pre-dialysis care than men. Women who received treatment for CAP were less likely than men to receive the appropriate AB's according to the 1993 guidelines for AB treatment of CAP. There were no significant treatment differences between men and women who had suffered a CVA or who had had a CABG. There were no gender differences in death for any of the diseases. There is little evidence of a significant gender bias in cardiovascular disease in Canada. A potential gender bias in the treatment of CVD patients needs to be explored further.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.628
Threshold uncertainty score0.968

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.359
GPT teacher head0.375
Teacher spread0.015 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes2
Has abstractyes

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