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Record W2623726585

Could dual anticoagulation with Rivaroxaban have precipitated a Spinal Epidural Hematoma: from independent mobility to paraplegia

2016· article· en· W2623726585 on OpenAlexaffvenue
Gautamn Sarwal, Charlotte Dandurand, Agnus Y Lee, Viet H. Vu

Bibliographic record

VenueUBC Faculty of Medicine medical journal · 2016
Typearticle
Languageen
FieldMedicine
TopicSpinal Hematomas and Complications
Canadian institutionsGF Strong Rehabilitation CentreUniversity of British Columbia
Fundersnot available
KeywordsMedicineRivaroxabanParaplegiaBleedAspirinSurgeryHematomaMagnetic resonance imagingStroke (engine)AnesthesiaSpinal cordAtrial fibrillationRadiologyWarfarinCardiologyInternal medicine
DOInot available

Abstract

fetched live from OpenAlex

A 81 year-old male, with atrial fibrillation (AF) and a prosthetic valve on aspirin and rivaroxaban, presented with acute back pain, limb weakness and paraplegia within six hours. Urgent spine magnetic resonance imaging (MRI) showed a massive epidural bleed from T1 – T12. A spontaneous spinal epidural hematoma (SSEH) was diagnosed. The patient was not a surgical candidate as the cord had infarcted and the risk of a fatal intra-operative bleed was high. He was ultimately transferred for rehabilitation on aspirin. His spinal cord injury was graded as T10 ASIA B. Anticoagulation was never restarted and the patient awaits an atrial appendage closure to reduce the risk of clot formation. To our knowledge, this is the first report of a long segment SSEH and adverse reaction to rivaroxaban with an unusually rapid and permanent neurologic sequelae.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.149
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.358
Teacher spread0.312 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes2
Has abstractyes

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