P1742Assessment of quality of life and ICD shock-related anxiety in patients with implantable cardioverter defibrillator: the PainFree SST study
Bibliographic record
Abstract
Funding Acknowledgements: Medtronic Background: The implantable cardioverter defibrillator (ICD) reduces mortality in patients at risk of sudden cardiac death. However, it is not known if the psychological status of ICD patients differs by geography. Purpose: The aim of this analysis is to compare Quality of Life (QoL) and ICD shock-related anxiety between ICD patients in Japan with those in other countries. Methods: The PainFree SST study was a prospective, multicenter, global study that enrolled 2770 patients including 181 from Japan. The EuroQol 5-D (EQ-5D) measures QoL and the Florida Shock Anxiety Scale (FSAS) measures ICD shock-related anxiety. These questionnaires were administered to the subjects bi-annually and monthly for 6 months after a shock. Results: Both the EQ-5D health score and FSAS score were higher in Japanese patients compared to patients in the other countries post-implant (EQ-5D: 70.4 ± 18.0 points vs 66.5 ± 19.3 points, p=0.012, FSAS: 20.8 ± 9.5 points vs 16.3 ± 7.8 points, p<0.0001), and stayed higher for the entire follow-up period. There were 964 shock episodes in 308 ICD patients during follow-up. The EQ-5D health score was significantly reduced after a shock (Japan: -18.1 points, p<0.0001; other countries: -7.5 points, p<0.0001) with a greater reduction in Japan (p=0.004). Recovery in the month following a shock was greater in Japan (+19.4 vs +3.7 points, p<0.0001). The FSAS score was significantly increased after a shock (Japan: +6.7 points, p<0.0001; other countries: +4.7 points, p<0.0001) and was similar between geographies (p=0.13). Recovery at 1 month was greater in Japanese patients (-6.1 vs -1.7 points, p=0.0008). Conclusion: Japanese patients were more anxious about a shock in spite of greater QoL, compared with those in other countries. After a shock, Japanese patients had a greater decrease in QoL and a similar increase in anxiety but recovery effects in both aspects were greater in the month after a shock.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".