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Record W2722297201 · doi:10.1021/acs.organomet.7b00373

Exploring the Influence of Phosphine Ligation on the Gold-Catalyzed Hydrohydrazination of Terminal Alkynes at Room Temperature

2017· article· en· W2722297201 on OpenAlexafffund
Nicolas L. Rotta‐Loria, Alicia J. Chisholm, Preston M. MacQueen, Robert McDonald, Michael J. Ferguson, Mark Stradiotto

Bibliographic record

VenueOrganometallics · 2017
Typearticle
Languageen
FieldChemistry
TopicCatalytic Alkyne Reactions
Canadian institutionsUniversity of AlbertaDalhousie University
FundersNatural Sciences and Engineering Research Council of CanadaKillam TrustsDalhousie University
KeywordsChemistryPhosphineCatalysisArylHydrateHydrazine (antidepressant)SilylationMedicinal chemistryEtherCombinatorial chemistryActivator (genetics)Polymer chemistryOrganic chemistry

Abstract

fetched live from OpenAlex

The synthesis and/or NMR/X-ray characterization of a new series of ( L )AuCl complexes is reported, featuring BippyPhos, AdJohnPhos, silyl ether based ligands including OTips-DalPhos, and PAd-DalPhos. These complexes, along with previously reported analogues featuring cataCXium-A, t BuJohnPhos, and Mor-DalPhos, were screened as precatalysts using LiB(C 6 F 5 ) 4 ·2.5Et 2 O as an activator in the hydrohydrazination of terminal aryl alkynes with hydrazine hydrate under unprecedentedly mild conditions (25 °C, 1 mol % Au). The precatalyst (cataCXium-A)AuCl proved to be particularly effective in such transformations, demonstrating useful scope.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.034
Threshold uncertainty score0.447

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.246
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2017
Admission routes2
Has abstractyes

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