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Record W2725704509 · doi:10.1186/s12977-017-0361-6

Tribute to Mark Wainberg

2017· article· en· W2725704509 on OpenAlexafffund
Eric J. Arts, Anne Gatignol, Andrew J. Mouland, Chen Liang, Matthias Götte, Hugo Soudeyns

Bibliographic record

VenueRetrovirology · 2017
Typearticle
Languageen
FieldMedicine
TopicHIV/AIDS drug development and treatment
Canadian institutionsUniversité de MontréalUniversity of AlbertaMcGill UniversityWestern University
FundersLady Davis Institute for Medical ResearchJewish General Hospital
KeywordsTributeMedicineComputational biologyComputer graphics (images)Computer scienceArt historyBiologyHistory

Abstract

fetched live from OpenAlex

As you will read below, most of his colleagues and former trainees wanted share personal memories of Mark intertwined with his research accomplishments and impact on HIV/AIDS treatment and care.Many of us forget Dr. Wainberg's many contribution to research because Mark did not live in the past and was always looking forward to a new drug, a new resistance pathway, and new possibilities for treatment.Many of us including myself fall victim of framing a question at a conference by discussing "our" past publication or data.Mark was never going to lecture you on his contribution to AZT resistance [1-3], discovery of 3TC inhibition and resistance [4-6], characterization of early events of reverse transcription [7, 8], description of early Vpu activity and CD4 downmodulation [9-12], the low fidelity/fitness of 3TC resistant virus [13-18], or description of alternative drug resistance pathways in non-subtype B HIV [19-21] (50+ articles).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.035
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.032
Threshold uncertainty score0.107

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.035
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0060.003
Scholarly communication0.0090.006
Open science0.0030.004
Research integrity0.0080.028
Insufficient payload (model declined to judge)0.0320.028

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.307
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes2
Has abstractyes

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