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Record W273308790

Can Hylan G-F 20 with corticosteroid meet the expectations of osteoarthritis patients?

2012· article· en· W273308790 on OpenAlexaboutno aff
Karen K. Briggs, Lauren M. Matheny, J Richard Steadman

Bibliographic record

VenuePubMed · 2012
Typearticle
Languageen
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineWOMACOsteoarthritisPhysical therapyCorticosteroidPatient satisfactionPain reliefHyaluronic acidInternal medicineAnesthesiaSurgeryAlternative medicine
DOInot available

Abstract

fetched live from OpenAlex

The purpose of this study was to document expectations and outcomes of active adults suffering from knee osteoarthritis (OA) who underwent treatment protocol of hyaluronic acid injection series with single injection of corticosteroid at initial injection. Our hypothesis was that patients would have functional improvement and pain relief following treatment, and that this treatment protocol will meet patients' expectations of treatment for knee OA. Forty-seven knees (range, 42-80 years) with a diagnosis of knee OA completed a self-administered questionnaire before and post injection series. Prior to injections, patients completed a validated expectation questionnaire and activity level questions. Following treatment, patients expected pain relief, to walk longer distances, and to increase activity level. Patients showed significant improvement in WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) pain subscale, comparing pre-injection and 6 months post-injection scores (P = .003) and overall WOMAC score (P = .038). SF-12 physical component significantly improved. Patients in this study expected to return to high levels of activity. Results showed significant improvement in pain relief and function. Our results supported that Hylan G-F 20 and corticosteroid are able to meet expectations of older patients with OA who desire to return to an active lifestyle. This study showed patient expectations do influence patient outcome scores and patient satisfaction.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.204
Teacher spread0.191 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2012
Admission routes1
Has abstractyes

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Same venuePubMed→Same topicOsteoarthritis Treatment and Mechanisms→French-language works237,207→