VITAMIN D INSUFFICIENCY AND MUSCULAR FATIGABILITY AMONG OLDER WOMEN
Bibliographic record
Abstract
Background: Vitamin D affects physical performance in older adults. Effects on muscles, notably on muscle strength, remain yet unclear. The objective of this cross-sectional study was to determine whether vitamin D insufficiency was associated with triceps brachii muscle fatigability in community-dwelling older women. Methods: A randomized subset of 744 women aged ≥75years from the French EPIDOS cohort was categorized into two groups according to vitamin D insufficiency (i.e., serum 25-hydroxyvitamin D concentration≤30ng/mL). Triceps brachii muscle fatigability was defined as the loss of strength between two consecutive maximal isometric voluntary contractions. Age, body mass index, comorbidities, use psychoactive drugs, physical activity, first triceps strength measure, hyperparathyroidism, serum concentrations of calcium, albumin and creatinine, season and study centers were used as potential confounders. Results: Triceps fatigability was more prevalent among women with vitamin D insufficiency (n=671) compared to the others (27.3% versus 12.3%, P=0.006). The serum concentration of 25OHD was inversely associated with the between-test change of triceps strength (adjusted β=-0.09, P=0.044). Vitamin D insufficiency was positively associated with triceps fatigability (adjusted OR=2.65, P=0.009). Conclusions: Vitamin D insufficiency was associated with muscle fatigability in this cohort of community-dwelling older women. This is a relevant new orientation of research toward understanding the involvement of vitamin D in muscle function.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".