EP-1198: Low risk breast cancer patients’ supportive care needs and perceptions of follow-up care options
Bibliographic record
Abstract
Material and MethodsBetween June 2010 and March 2016, 25 patients with locally advanced breast cancer, who underwent modified radical mastectomy, IR, and PMRT were treated at our center.RT was delivered to the chest wall ± nodal areas according to stage, with 6MV and total dose of 50 Gy in 25 fractions.Complications were scored following the CTCAE 4.0 criteria.The capsular contracture was evaluated following the Baker classification.Cosmesis was rated as either acceptable or unacceptable to the patient. ResultsThe mean age was 46.7 years (range, 33-65).A total of 20 patients underwent tissue expander and 5 underwent implant (TE/I).Median follow-up (from the start of RT) for all patients was 18 months (m) (4-48m).40% of the patients were never smokers; 28% were smokers and 32% ex-smokers during RT.10% and 68% of the patients received neoadjuvant and adjuvant chemotherapy respectively, and 17 patients taking Tamoxifen during RT.After surgery the complications occurred in 15/25 patients: 7 with capsulitis grade (G) 2; 2 with capsulitis G3-4; 3 with cutaneous suffering and mastitis, extrusion and hematoma were presented in 1 patient each.Complications post surgery in 2 patients as were hematoma and extrusion required additional surgery and delayed beginning of RT.All patients completed the RT course without major complications.During RT the only complication presented was skin erythema (SE) G1-2 seen in 20 (80%) and G3 in just 5 patients which were all smokers.During the follow up the major complications were: capsulitis G3 in 5 patients and G4 in 1; skin hyperpigmentation was presented in 4 patients, cutaneous thinning in 6 and 1 patient presented relevant lung toxicity.At the end of the follow-up, TE Exchange have been realized in 12 patients with a mean time after RT of 14,3m (9-22), 3 of them are pending of a new corrective surgery, specialy for improve cosmetic outcomes.We reported capsulitas G4 in 2 patients after the Exchange; both were smokers and 1 of them presented extrusion before RT, therefore she was operated twice.Acceptable cosmesis was reported in 60% of the patients Conclusion Our experiences is limited but in our patients undergoing PMRT, RT can be safely delivered after IR, with a low complication rate and good patient satisfaction.In our patients major complications occurred before RT.Further studies are needed to define the factors that may be related to worse aesthetic results.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.006 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.010 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".