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Record W2735935643 · doi:10.1039/9781788010528-00200

Aptamer-based Sensing Techniques for Food Safety and Quality

2017· book-chapter· en· W2735935643 on OpenAlexaff
Daniel Goudreau, McKenzie Smith, Erin M. McConnell, Annamaria Ruscito, Ranganathan Velu, Joshua P Callahan, Maria C. DeRosa

Bibliographic record

Venuenot available
Typebook-chapter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced biosensing and bioanalysis techniques
Canadian institutionsCarleton University
Fundersnot available
KeywordsAptamerFood safetyBiosensorBiochemical engineeringNanotechnologyOligonucleotideFood qualityBiotechnologyRisk analysis (engineering)ChemistryBiologyEngineeringBusinessFood scienceMaterials scienceBiochemistry

Abstract

fetched live from OpenAlex

Food safety is a growing public health concern worldwide. The need to detect unsafe levels of food contaminants such as chemical compounds, toxins and pathogens prompts new technology and advances in biosensing for food safety. Although current detection methods are able to detect such contaminants with a high level of selectivity and sensitivity, these methods continue to lack practical application. A reliable, easy-to-use, inexpensive detection method that can be used quickly and on-site is a necessity, especially for contaminants that primarily affect food commodities in developing countries. Aptamers are single-stranded oligonucleotides capable of binding a specific target molecule with a high degree of affinity and selectivity. These molecular recognition elements can be selected to bind selectively to a specific target molecule, ranging from small molecules to whole cells. This allows aptamers to be used as the recognition components for food-safety related biosensors. This chapter will review recent literature in aptamers for food-safety related target molecules, and will focus on the incorporation of these aptamers in sensitive and practical biosensors for a variety of food products.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.016
Threshold uncertainty score0.053

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0000.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0160.014

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.316
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2017
Admission routes1
Has abstractyes

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