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Record W2736129197 · doi:10.1016/s0140-6736(17)31444-7

Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial (NeoPIns)

2017· article· en· W2736129197 on OpenAlexaff
Martin Stocker, Wendy van Herk, Salhab el Helou, Sourabh Dutta, Matteo Fontana, Frank A B A Schuerman, Rita K. van den Tooren-de Groot, Jantien W. Wieringa, Jan Janota, Laura H van der Meer-Kappelle, Rob Moonen, Sintha D. Sie, Esther de Vries, Albertine E. Donker, Urs Zimmerman, Luregn J. Schlapbach, Amerik C. de Mol, Angelique Hoffman-Haringsma, Madan Roy, Maren Tomaske, René F. Kornelisse, Juliette van Gijsel, Eline G. Visser, Sten P. Willemsen, Annemarie M. C. van Rossum, Ahmed K. Bakry, Kaarthigeyan Kalaniti, David Pogorzelski, S Alliston, M Roy, Vijaylaxmi Grey, Kristin Hauff, S. L. Hill, Saranya Kittanakom, Magda Višňovská, David Glauser, Mathias Nelle, FABA Schuerman, SD Sie, Mirjam M. van Weissenbruch, FAM van den Dungen, Marc Strik, HK van den Tooren-de, Groot A van Rossum, Manou R. Batstra, LH van der Meer-Kappelle, AC de Mol, J Bolt-Wieringa, Daniel Stok, Sarah Donker, IPE Gondriet, S Hoekstein, M Hofhuis, WCJ Hop, L de Ligt, B Manai, YB de Rijke, Satu J. Siiskonen, Jolanda van der Velden, E Visser, J Asch van Wijk, GJ van der Geijn, Angelique Haringsma, Peter Andriessen, MAC Broeren

Bibliographic record

VenueThe Lancet · 2017
Typearticle
Languageen
FieldMedicine
TopicNeonatal and Maternal Infections
Canadian institutionsMcMaster UniversityHamilton Health SciencesSt. Joseph’s Healthcare HamiltonMcMaster Children's Hospital
FundersSophia FoundationErasmus+Fonds NutsOhraThrasher Research Fund
KeywordsMedicineProcalcitoninSepsisPediatricsGestational ageRandomized controlled trialNeonatal sepsisAntibioticsInternal medicinePregnancy

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.009
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.003
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0030.005
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.346
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations268
Published2017
Admission routes1
Has abstractno

Explore more

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