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Record W2738004873 · doi:10.1111/jfbc.12392

Prospects of brown seaweed polysaccharides (BSP) as prebiotics and potential immunomodulators

2017· article· en· W2738004873 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueJournal of Food Biochemistry · 2017
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicSeaweed-derived Bioactive Compounds
Canadian institutionsNova Scotia Department of AgricultureUniversity of OttawaDalhousie UniversityCape Breton University
FundersMitacs
KeywordsPrebioticBiologyFunctional foodPopulationGut floraPolysaccharideBiotechnologyFood scienceImmune systemBiochemistryMedicineImmunology

Abstract

fetched live from OpenAlex

Prebiotics enhance immune response through the modulation of intestinal microbial activities, production of short chain fatty acids (SCFA), direct interaction with toll-like receptors and mucin production. These non-digestible food components are known to be resistant to enzymatic hydrolysis by digestive enzymes and are utilized as carbon source for the growth of beneficial bacteria population through the process of fermentation. Brown seaweed polysaccharides (BSP) have been described as emerging prebiotics due to their potential to stimulate gut microbiota activities at in vitro and in vivo stages. This review therefore examines evidence of the relationship between the prebiotic capacity of BSP, their structure, extraction, and possible mechanisms of immunomodulation. Practical applications Bio-functional ingredients have been widely explored for numerous health benefits. Of interest to this review are polysaccharides of brown seaweed which have great prebiotic prospects. Prebiotics are important bio-functional ingredients having the potential to improve immune health. An understanding of the prebiotic and immunomodulatory potential of BSP provides the food industry a novel alternative source of prebiotics. Excerpts from this review will provide background knowledge and advance scientific research into prospects of BSP as prebiotics and a possible commercialization of BSP products.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.105
Threshold uncertainty score0.273

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.222
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it