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Record W2739023078

TRANSLATIONAL RESEARCH: ETHICAL CONSIDERATIONS

2017· article· en· W2739023078 on OpenAlexvenueno aff
Yiqing Dong

Bibliographic record

VenueSound Ideas (University of Puget Sound) · 2017
Typearticle
Languageen
FieldHealth Professions
TopicEthics in medical practice
Canadian institutionsnot available
Fundersnot available
KeywordsEngineering ethicsEngineering
DOInot available

Abstract

fetched live from OpenAlex

Translational research (TR) is a new categorization for the efforts of biomedical research and emphasizes efficiency in achieving population health improvements through the application of basic science knowledge in clinical practice. It will be argued that the current emphasis on speed and collaboration with industry established by national policies provides challenges to maintaining the integrity of scientific research. There is no agreed upon definition of TR and the current standard of judging the success of TR focuses on product production. I propose that the principles of beneficence and responsive justice should be used to inform the values of TR and to produce an agreed upon definition for TR. I will also suggest possible actions and changes to help incorporate the principles of beneficence and responsive justice into the translational framework that include greater reflection throughout the translational process about its priorities, increased role of implementation research, and the communication of negative results in addition to positive results.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.392
metaresearch head score (Gemma)0.441
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.392
Threshold uncertainty score0.750

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3920.441
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0040.003
Bibliometrics0.0030.003
Science and technology studies0.0100.064
Scholarly communication0.0210.018
Open science0.0070.013
Research integrity0.0540.061
Insufficient payload (model declined to judge)0.0070.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.383
GPT teacher head0.543
Teacher spread0.160 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

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