A review of international clinical practice guidelines for the use of oxygen in the delivery room resuscitation of preterm infants
Bibliographic record
Abstract
Abstract Aim To collate and assess international clinical practice guidelines ( CPG ) to determine current recommendations guiding oxygen management for respiratory stabilisation of preterm infants at delivery. Methods A search of public databases using the terms ‘clinical practice guidelines’, ‘preterm’, ‘oxygen’ and ‘resuscitation’ was made and complemented by direct query to consensus groups, resuscitation expert committees and clinicians. Data were extracted to include the three criteria for assessment: country of origin, gestation and initial FiO 2 and target SpO 2 for the first 10 minutes of life. Results A total of 45 CPG s were identified: 36 provided gestation specific recommendations (<28 to <37 weeks) while eight distinguished only between ‘preterm’ and ‘term’. The most frequently recommended initial FiO 2 were between 0.21 and 0.3 (n = 17). Most countries suggested altering FiO 2 to meet SpO 2 targets recommended by expert committees, However, specific five‐minute SpO 2 targets differed by up to 20% (70–90%) between guidelines. Five countries did not specify SpO 2 targets. Conclusion CPG recommendations for delivery room oxygen management of preterm infants vary greatly, particularly in regard to gestational ages, initial FiO 2 and SpO 2 targets and most acknowledge the lack of evidence behind these recommendations. Sufficiently large and well‐designed randomised studies are needed to inform on this important practice.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.009 | 0.225 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".