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Effect of electroacupuncture on postoperative cognitive function in elderly patients undergoing carotid endarterectomy

2016· article· en· W2746607512 on OpenAlexaboutno aff
Shunyan Lin, Yin Zhenglu, Ju Gao, Yang Liuqing, Shen Wenrui

Bibliographic record

VenueZhonghua mazuixue zazhi · 2016
Typearticle
Languageen
FieldNeuroscience
TopicAnesthesia and Neurotoxicity Research
Canadian institutionsnot available
Fundersnot available
KeywordsElectroacupunctureMedicineCarotid endarterectomyMontreal Cognitive AssessmentZusanliSufentanilPostoperative cognitive dysfunctionAnesthesiaEndarterectomyBrain-derived neurotrophic factorInternal medicineCognitionSurgeryNeurotrophic factorsAcupunctureStenosisDementiaPathology

Abstract

fetched live from OpenAlex

Objective To evaluate the effect of electroacupuncture on postoperative cognitive function in elderly patients undergoing carotid endarterectomy. Methods Fifty patients of both sexes, aged ≥65 yr, of American Society of Anesthesiologists physical status Ⅱ or Ⅲ, with the educational level ≥ the level of primary school, scheduled for elective unilateral carotid endarterectomy, were divided into 2 groups (n=25 each) using a random number table: control group (group C) and electroacupuncture group (group EA). In group EA, electroacupuncture (frequency 2/100 Hz, intensity 5-12 mA) of Baihui (GV20), Neiguan (PC6) and Zusanli (ST36) was performed throughout surgery starting from 30 min before operation, and then general anesthesia was performed.General anesthesia was performed directly in group C. Before operation (T0), at the end of operation (T1) and at 24 h after operation (T2), blood samples were collected from the internal jugular vein for determination of plasma S-100β protein, tumor necrosis factor-α and brain-derived neurotrophic factor (BDNF) concentrations by enzyme-linked immunosorbent assay.The cognitive function was assessed using Montreal Cognitive Assessment at T0, 2 and at 3 and 7 days after operation (T3, 4). Results Compared with group C, the Montreal Cognitive Assessment scores were significantly increased at T2-4, the plasma S-100β protein and tumor necrosis factor-α concentrations were significantly decreased at T1, 2, and the plasma BDNF concentrations were significantly increased at T2 in group EA (P<0.05). Conclusion Electroacupuncture can improve postoperative cognitive function in the elderly patients undergoing carotid endarterectomy, which may be related to inhibition of inflammatory responses, promotion of BDNF production and reduction of brain injury. Key words: Electric stimulation therapy; Endarterectomy, carotid; Cognition disorders; Aged

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.075
Threshold uncertainty score0.746

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.271
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2016
Admission routes1
Has abstractyes

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