Abstract 3118: Star: Solitaire Fr Thrombectomy For Acute Revascularisation, International Clinical Evaluation Of The Solitaire™ Fr Used In The Treatment Of Patients With Acute Ischemic Stroke
Bibliographic record
Abstract
Objective: The aim of the study is to evaluate mechanical thrombectomy with the Solitaire FR when used according to hospitals’ stroke protocols (direct intra-arterial, bridging IV/IA and endovascular after failed or contraindicated IV lysis). Design: Single arm, observational, multi-center, prospective study with consecutive inclusion. Sample size: The target number of patients is 200 in 20 centers with a maximum of 30 patients per center. Centers: 2 centers in Switzerland, 9 centers in Germany, 1 in Austria, 4 centers in Spain, 1 in Canada, 1 in Australia, 1 in Portugal, 1 in France. Study population: Patients presenting with acute ischemic stroke in anterior circulation, aged 18-85 years. Baseline NIH stroke scale between 8 and 30. Pre-stroke mRS ≤2. Treatment initiated within 8 hours of symptom onset. Meet specific imaging criteria based on ASPECT score. Interventions: Patients will be treated with the Solitaire FR Revascularization Device used as 1st intention device in routine practice. Endpoints: Primary endpoint will be recanalization of the occluded vessel, core lab reviewed, using TICI score with TICI 2b and 3 defined as successful recanalization. Correspondent TIMI scores will be determined for comparison with other studies. Safety endpoint: Adverse events related to the device or the procedure. All adverse events will be reviewed by an independent clinical event committee. Secondary endpoints: Time to revascularization, NIHSS at 90 days, mRS at 90 days, incidence of symptomatic intracranial hemorrhage, immediate flow reperfusion. Trial status: Enrollment is ongoing. There are currently 7 enrolling centers with a total of 37 patients. Registers: ClinicalTrials.gov NCT01327989
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.005 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".