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E55. RHEUMATOLOGISTS’ PERCEPTIONS IMPACT CLINICAL DECISION MAKING WHEN COMMENCING NEW PATIENTS WITH RHEUMATOID ARTHRITIS ON METHOTREXATE

2017· article· en· W2753628065 on OpenAlexaff
Holly Hope, Kimme L Hyrich, Suzanne Verstappen, Lis Cordingley

Bibliographic record

VenueLara D. Veeken · 2017
Typearticle
Languageen
FieldMedicine
TopicRheumatoid Arthritis Research and Therapies
Canadian institutionsArthritis Research Centre of Canada
FundersBristol-Myers Squibb
KeywordsMedicineRheumatoid arthritisMethotrexateRheumatologyPhysical therapyInternal medicineClinical decision makingFamily medicine

Abstract

fetched live from OpenAlex

Background: Very little is known about the medication and treatment beliefs of rheumatologists and how these beliefs might impact practice. In a preceding qualitative study the authors identified a number of factors that may contribute to the discussion and commencement of methotrexate (MTX) for the treatment of rheumatoid arthritis (RA). This study aimed to examine if rheumatologists’ decision to discuss or commence MTX during the initial consultation associated with the gender, perceived emotional preparedness, or perceived prior knowledge of the patient. Methods: This was the second phase of a sequential, exploratory mixed methods designed study. An online survey was designed and refined based on interviews with UK rheumatologists. The questionnaire included a factorial survey. Two patient vignettes manipulated the following patient factors; male/female, emotionally prepared/unprepared and no/negative prior knowledge. Rheumatologists were asked to judge for each vignette the likelihood of Commencing MTX (0=very unlikely – 10=very likely). Rheumatologists, rated how important it was to discuss specific pieces of MTX information (4=very important – 1 = not important at all), the Discussing MTX variable was obtained from the mean value. A MANCOVA tested if each level of gender × patient preparedness × prior knowledge, controlling for individual differences in scoring, associated with 1) Commencing MTX and 2) Discussing MTX. Pillai’s Trace (V) measured the overall fit of the model and the main and interaction effects on the dependent variables. Post hoc, univariate analyses were conducted to identify the nature of effects (p <0.05).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.045
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.054

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.045
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0020.003
Scholarly communication0.0040.002
Open science0.0010.002
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0140.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.377
Teacher spread0.334 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2017
Admission routes1
Has abstractyes

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