Ultrasound-guided radiofrequency ablation of genicular nerves of knee for relief of intractable pain from knee osteoarthritis: a case series
Bibliographic record
Abstract
INTRODUCTION: The knee arthroplasty is the best option for patients with advanced osteoarthritis who have failed all other conservative options, but regrettably many patients fail to undergo surgery due to co-morbidities or other reasons. So, new alternative modes are always in demand for these patients. METHODS: The ultrasound-guided radiofrequency ablation (RFA) of all the genicular nerves of knee joint was done in patients with grade III and IV osteoarthritis of knee joint, with severe pain (numerical rating scale (NRS) > 7) who had failed conservative management and intra-articular injections after a positive genicular nerve block with local anaesthetics. The demographics, pain intensity measured in NRS, Oxford Knee Score (OKS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and quality of life measured by 36-Item Short Form Health Survey (SF-36) questionnaire was measured at baseline and at regular intervals. RESULTS: The average age of the patients was 61.50 ± 6.75 years. There was significant improvement in pain intensity at rest, movement and on weight bearing from 8.75 ± 0.5, 9.0 ± 0.0, and 9.0 ± 0.0 at baseline to 2.38 ± 0.51, 3.75 ± 0.46, and 4.13 ± 0.35 at 1 month and 3.13 ± 0.64, 4.38 ± 0.51, and 4.63 ± 0.51 at 6 months after the procedure, respectively (p value <0.05). The OKS had improved from 7.75 ± 1.25 at baseline to 28.88 ± 2.53 and 28.13 ± 1.80 at 1 and 6 months, respectively, after the procedure (p value <0.05). The WOMAC score had also improved significantly from 77.75 ± 4.34 at baseline to 38.38 ± 5.82 and 39.25 ± 5.12 at 1 and 6 months, respectively (p value <0.05). There was also significant improvement in the quality of life after the procedure (p value <0.05). CONCLUSION: Ultrasound-guided RFA of genicular nerves of knee joint is a good alternative option for patients who are having severe pain and disability from knee osteoarthritis and gives a long-lasting pain relief for more than 6 months.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.005 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".