P02.04: Axial and coronal views of the vermian primary fissure assist in the diagnosis of vermian dysgenesis
Bibliographic record
Abstract
Background: The primary fissure is a landmark for anatomical assessment of the vermis. Deficient development of vermian lobules (not limited to the inferior vermis) is linked to adverse neurodevelopmental outcome. Previous studies have focused on its appearance in the median sagittal plane. To our knowledge, the appearance of the primary fissure in axial and coronal planes has not been studied. Hypothesis: 1. The normal primary fissure can be visualised consistently on routine axial and coronal views through the cerebellum. 2. The abnormal position or appearance of the primary fissure in these planes indicates abnormal vermian development. Scans in 224 consecutive fetuses with gestational age between 19 and 23 weeks, in whom there was no suspicion of vermian abnormality, were retrospectively reviewed to determine the reliability of documenting the primary fissure on routine views of the cerebellum. Secondly, 30 cases with suspected vermian abnormalities and known outcome were analysed to assess position and appearance of the primary fissure. The primary fissure was documented in 215/224 (96%) of normal subjects. It was equidistant from the anterior and posterior border of the vermis in all cases in which the primary fissure was visible. In 6 cases of megacisterna magna and 4 cases of Blake cyst, in whom postnatal outcome was normal, the appearance and location of the primary fissure were normal. In cases with abnormal outcome, the primary fissure could not be visualised or was in an abnormal location in 18/20 (90%). Confirmation of a normal primary fissure on axial and coronal views between 19 and 23 weeks assists in documenting that the vermis is anatomically normal. An abnormal appearance of the primary fissure increases suspicion that vermian lobular dysplasia is present.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.007 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".