OP11.06: Outcomes of term born neonates after an episode of preterm labor
Bibliographic record
Abstract
To determine if a short cervical length (CL) by transvaginal ultrasonography (TVUS) in women who present with threatened preterm labour (TPTL) but deliver at term predicts small-for-gestational age (SGA) neonates or adverse perinatal outcome. This retrospective cohort study included women with singleton gestations who underwent TVUS assessment of CL between 16 and 30 weeks' gestation for TPTL, but delivered at term(≥37 weeks' gestation), March 2006 to Dec 2015. Comparison was between women who had a short CL (<2.5 cm) and those with a normal CL (≥2.5 cm). Primary outcomes were birthweight (BW) <10% and <5%. Secondary outcomes included adverse perinatal outcome (low Apgar score, low cord arterial pH, bacterial infection, NICU admission or end organ dysfunction). Multiple logistic regression (MLR) was used to adjust for potential confounders to determine if CL independently predicted the outcomes of interest. A total of 205 women were included. Women with a short CL but delivered at term (n = 25) were more likely to have an SGA infant with BW 3% to 5%, compared to women with a normal CL who delivered at term (n = 180) (8.0% vs 0.6%, p = 0.040). Compared to women with a normal CL, those with a short CL were more likely to have a history of a LEEP procedure (28.0% vs 8.9%, p = 0.011), and were more likely to have received betamethasone for fetal lung maturation (92.0% vs 21.2%, p < 0.0001). Infants born to women with a short CL were born at a slightly earlier gestation (38 wks 4 days vs 39 wks 3 days, p < 0.0001). There were no differences in BW <10% (8.0% short CL vs 5.0% normal CL, p = 0.63) or adverse perinatal outcome (4.0% short CL vs 3.3% normal CL, p = 1.00). MLR found that short CL was an independent predictor for BW 3% to 5% (OR 3.94, 95% CI 1.16-13.33). Women who deliver at term after an episode of TPTL, and had a short cervical length are more likely to have an SGA infant with BW 3% to 5%, compared to women who deliver at term after an episode of TPTL but had a normal cervical length. Further research is needed to assess this association and its possible pathophysiology.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".