Abstract 11979: Relationship between the QT Interval and Outcome in Low-Flow Low-Gradient Aortic Stenosis With Low LVEF
Bibliographic record
Abstract
Background: The QT interval has been shown to be associated with cardiovascular events. There is no data available on the association between the QT interval and left ventricular (LV) function and on its impact on prognosis in patients with low LV ejection fraction (LVEF), low-flow, low-gradient (LF-LG) aortic stenosis (AS). The objectives of this study were to examine the relationship between the corrected QT interval (QTc) and LV function and outcome in patients with LF-LG AS and low LVEF. Methods: Ninety-three patients (73±10 years; 74% men) with LF-LG AS (i.e. mean gradient [MG] <40 mmHg and indexed aortic valve area [AVAi] ≤0.6 cm2/m2) and reduced LVEF (≤40%) were prospectively included in this analysis and 63 (68%) of them underwent aortic valve replacement (AVR) within 3 months following inclusion. QTc was calculated with the Bazett formula. Prolonged QTc was defined as QTc> 450 ms in men and >470 ms in women. The severity of AS was assessed by the projected AVA (AVAproj) at normal flow rate. LV global longitudinal strain (GLS) was measured by 2D speckle tracking and expressed in absolute value
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".