Targeted mass treatment for syphilis with oral azithromycin in Vancouver, Canada
Bibliographic record
Abstract
A recent paper by Rekart and colleagues (1) presented the findings of a mass treatment intervention to eliminate an outbreak of syphilis in Vancouver, British Columbia. Following several years of very low reported infectious syphilis rates in British Columbia (less than 0.5 per 100 000 population (2), with the majority of cases acquired overseas, there was a marked increase in numbers of reported cases from mid-1997 onwards. This was largely due to a geographically localised outbreak in Vancouver’s disadvantaged downtown eastside area, with rates reaching 126 per 100 000 in this area in 1999. Sixty five percent of the 277 cases reported were among persons who had contact with a potential source of their infection in or from this area. The outbreak was spread mainly through heterosexual contact, with 42% of patients associated with the sex industry (18% sex workers and 24% clients, (2)). Only 6% of cases were in men who have sex with men (MSM). Given high HIV rates among among injection drug users (IDUs) in Vancouver, and the frequent involvement of female IDUs involved in sex work, rising syphilis incidence could facilitate the spread of HIV infection both within the disadvantaged population of Vancouver’s downtown eastside itself, as well as outwards from sex workers through clients into the general population (2).
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".