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Record W2763663753 · doi:10.1016/j.jaci.2017.09.015

Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy

2017· review· en· W2763663753 on OpenAlexafffund
Yuka Asai, Aïda Eslami, C. D. van Ginkel, Loubna Akhabir, Ming Wan, George Ellis, Moshe Ben‐Shoshan, David Martino, Manuel A. R. Ferreira, Katrina J. Allen, Bruce Mazer, Hans de Groot, Nicolette W. de Jong, Roy N. Gerth van Wijk, A. E. J. Dubois, Rick Chin, Stephen Cheuk, Joshua Hoffman, Eric Jörgensen, John S. Witte, Ronald B. Melles, Xiumei Hong, Xiaobin Wang, Jennie Hui, Arthur W. Musk, Michael Hunter, Gerard H. Koppelman, Andrew J. Sandford, Ann E. Clarke, Denise Daley

Bibliographic record

VenueJournal of Allergy and Clinical Immunology · 2017
Typereview
Languageen
FieldMedicine
TopicFood Allergy and Anaphylaxis Research
Canadian institutionsMcGill University Health CentreMontreal Children's HospitalUniversity of British ColumbiaUniversity of CalgaryMcGill UniversityQueen's University
FundersNational Cancer InstituteNIH Office of the DirectorNational Institute on AgingCanadian Allergy, Asthma and Immunology FoundationStichting voor de Technische WetenschappenNational Health and Medical Research CouncilTeva Pharmaceutical IndustriesMedical Research CouncilCanadian Institutes of Health ResearchMcGill University Health CentreNational Institutes of HealthNederlandse Organisatie voor Wetenschappelijk OnderzoekNutricia Research FoundationHealthwayCommon FundGlaxoSmithKlineNational Institute of Mental HealthChildren's Hospital FoundationFood Allergy CanadaMichael Smith Health Research BCMcGill UniversityU.S. Department of DefenseSanofiNational Heart, Lung, and Blood InstitutePfizerCanadian Dermatology Foundation
KeywordsSingle-nucleotide polymorphismGenome-wide association studyGeneticsBiologyGenetic associationCandidate geneQuantitative trait locusLinkage disequilibriumPopulationGeneGenotypeMedicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.008
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.790
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.008
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0060.003
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.256
GPT teacher head0.450
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations81
Published2017
Admission routes2
Has abstractno

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