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Record W2765239727 · doi:10.1021/acssuschemeng.7b03192

High Voltage Electrical Treatments To Improve the Protein Susceptibility to Enzymatic Hydrolysis

2017· article· en· W2765239727 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueACS Sustainable Chemistry & Engineering · 2017
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMicrobial Inactivation Methods
Canadian institutionsUniversité Laval
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsEnzymatic hydrolysisChemistryNutraceuticalPopulationHydrolysisNucleophileEnzymeBiotechnologyFood scienceBiochemistryBiologyCatalysis

Abstract

fetched live from OpenAlex

The rapidly growing global population raises important issues associated with the environmental burden imposed by agri-food and biotechnological industries to satisfy the increasing demand of high-quality food and nutraceuticals. Hence, the introduction of emergent ecoefficient technologies in the bioproduction lines is inevitable. The present study deals with environmentally sustainable high voltage electrical treatments (HVETs)—pulsed electric field (PEF) and electrical arc—to improve the susceptibility of β-lactoglobulin to enzymatic hydrolysis. This protein was chosen due to its high excess in dairy industry coproducts, which must be valorized. The results demonstrate that, at the optimal HVET duration of 10 min (voltage = 40 kV and pulse frequency = 0.5 Hz), the degree of hydrolysis can be improved by 80% and 66% for the PEF and electrical arc, respectively. This fact is related to the ability of HVET to induce the active sites formation in protein molecule for the nucleophilic enzymatic action, which leads to the release of bioactive and functionally active peptides. Moreover, it is possible to control the selectivity of hydrolysis by varying the HVET modes. Thus, the implication of HVET to valorize the dairy whey proteins by their enzymatic hydrolysis can significantly improve the process ecoefficiency.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.015
Threshold uncertainty score0.953

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.246
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it