Stability of the helical configuration of an intrinsically straight semiflexible biopolymer inside a cylindrical cell
Bibliographic record
Abstract
We examine the effects of the external force, torque, temperature, confinement, and excluded volume interactions (EVIs) on the stability of the helical configuration of an intrinsically straight semiflexible biopolymer inside a cylindrical cell. We find that to stabilize a helix, the confinement from both ends of the cell is more effective than a uniaxial force. We show that under a uniaxial force and in absence of confinement from bottom of the cell, a stable helix is very short. Our results reveal that to maintain a low pitch helix, a torque acting at both ends of the filament is a necessity, and the confinement can reduce the required torque to less than half making it much easier to form a stable helix. Moreover, we find that thermal fluctuations and EVIs have little impact on the stability of a helix. Our results can help understand the existence of the helix and ring configurations of some semiflexible biopolymers, such as MreB homologs, inside a rod-shaped bacteria.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".