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The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

2017· article· en· 875 citations· W2773514102 on OpenAlex· 10.1038/nm.4439

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.018
GPT teacher head0.347
Teacher spread
0.328 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Medicine
Topic
Acute Myeloid Leukemia Research
Field
Medicine
Canadian institutions
Canada's Michael Smith Genome Sciences Centre
Funders
National Institute of General Medical SciencesNational Cancer Institute
Keywords
BiologyKRASNeuroblastoma RAS viral oncogene homologMyeloid leukemiaCancer researchGeneticsDNA methylationSTK11GenemicroRNAMutationGene expression
Has abstract in OpenAlex
no