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Record W2778546216 · doi:10.3732/apps.1700079

Using Herbarium‐Derived DNAs to Assemble a Large‐Scale DNA Barcode Library for the Vascular Plants of Canada

2017· article· en· W2778546216 on OpenAlex
Maria Kuzmina, Thomas Braukmann, Aron J. Fazekas, Sean W. Graham, Stephanie deWaard, Anuar Rodrigues, B. A. Bennett, Timothy A. Dickinson, Jeffery M. Saarela, Paul M. Catling, Steven G. Newmaster, Diana M. Percy, Erin Fenneman, Aurélien Lauron‐Moreau, Bruce A. Ford, Lynn J. Gillespie, Subramanyam Ragupathy, Jeannette Whitton, Linda Jennings, Deborah A. Metsger, Connor P Warne, Allison Brown, Elizabeth Sears, Jeremy R deWaard, Evgeny Zakharov, Paul D. N. Hebert

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueApplications in Plant Sciences · 2017
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic diversity and population structure
Canadian institutionsUniversité de MontréalCanadian Museum of NatureRoyal Ontario MuseumUniversity of ManitobaCanada Research ChairsYukon UniversityUniversity of New BrunswickUniversity of TorontoAgriculture and Agri-Food CanadaUniversity of British ColumbiaUniversity of Guelph
FundersGovernment of Canada
KeywordsBiologyBarcodeDNA barcodingHerbariumBiomeDNA sequencingGenetic genealogyEvolutionary biologyBotanyEcologyGeneticsDNA

Abstract

fetched live from OpenAlex

Premise of the study: Constructing complete, accurate plant DNA barcode reference libraries can be logistically challenging for large‐scale floras. Here we demonstrate the promise and challenges of using herbarium collections for building a DNA barcode reference library for the vascular plant flora of Canada. Methods: Our study examined 20,816 specimens representing 5076 of 5190 vascular plant species in Canada (98%). For 98% of the specimens, at least one of the DNA barcode regions was recovered from the plastid loci rbcL and matK and from the nuclear ITS2 region. We used beta regression to quantify the effects of age, type of preservation, and taxonomic affiliation (family) on DNA sequence recovery. Results: Specimen age and method of preservation had significant effects on sequence recovery for all markers, but influenced some families more (e.g., Boraginaceae) than others (e.g., Asteraceae). Discussion: Our DNA barcode library represents an unparalleled resource for metagenomic and ecological genetic research working on temperate and arctic biomes. An observed decline in sequence recovery with specimen age may be associated with poor primer matches, intragenomic variation (for ITS2), or inhibitory secondary compounds in some taxa.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.297
Threshold uncertainty score0.977

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.274
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it