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Record W2781122577 · doi:10.1107/s0108767317096544

Structural and functional studies of strigolactone receptors of <i>Striga hermonthica</i>, its adaptation and evolution

2017· article· en· W2781122577 on OpenAlexaff
Amir Arellano-Saab, P.J. Stogios, Alexei Savchenko, Peter McCourt

Bibliographic record

VenueActa Crystallographica Section A Foundations and Advances · 2017
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPlant Parasitism and Resistance
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsStrigaStriga hermonthicaAdaptation (eye)BiologyBotanyNeuroscienceGermination

Abstract

fetched live from OpenAlex

Striga spp. is a genus of obligate root-parasitic plants, with the ability to deplete host roots from water, carbohydrates, and other essential nutrients. There are around 30-35 species within the genus, and at least 80% of them are found in Africa. The most destructive species found in Africa is Striga hermonthica, with the ability to parasite major food crops, such as rice, millet, maize, and sorghum, producing high yield losses ranging from 30% to 100% of the crops (Berner, Kling, & Singh, 1995). Nowadays, the most common method to eliminate the parasitic plants is hand weeding, which is time-consuming, labour-intensive, and not very effective. It is thought that a complete understanding of the germination mechanism of Striga is necessary to develop targeted strategies to attack this weed. It has been proven that the germination of parasitic plants such as Striga and Orobanche is triggered by chemical factors called strigolactones (Toh et al., 2015). Although the strigolactone receptor system has been studied, it is not completely characterized yet. It is known that the system is composed of 11 different receptors and each of them presents variable sensitivities to strigolactones. Several attempts to crystallize these receptors have been made, but only two structures have been reported so far, ShHTL3 (Xu et al., 2016) and ShHTL5 (Toh et al., 2015). It is essential to reveal the structural differences between the ShHTL receptors to understand its particular role in the strigolactone detection and establish the molecular basis for this detection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.262
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

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