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Record W2781880236 · doi:10.1182/blood-2017-07-796151

ABO zygosity, but not secretor or Fc receptor status, is a significant risk factor for IVIG-associated hemolysis

2018· letter· en· W2781880236 on OpenAlexafffund
Donald R. Branch, Åsa Hellberg, Christine W. Bruggeman, Jill R. Storry, Darinka Sakac, Megan Blacquiere, Tik Nga Tong, Emeralda Burke, Beth Binnington, Nagina Parmar, Lorna Sampson, Kezia Willie, Chantal Armali, Aziz Jiwajee, Lani Lieberman, Vinçent Laroche, Jeannie Callum, Yulia Lin, Nadine Shehata, Katerina Pavenski, Wendy Lau, Barbara Hannach, Taco W. Kuijpers, Martin L. Olsson, Christine Cserti‐Gazdewich, Jacob Pendergrast

Bibliographic record

VenueBlood · 2018
Typeletter
Languageen
FieldMedicine
TopicBlood groups and transfusion
Canadian institutionsHospital for Sick ChildrenHôpital de l'Enfant-JésusSt. Michael's HospitalSunnybrook Health Science CentreMount Sinai HospitalCanadian Blood ServicesHealth Sciences CentreUniversity Health NetworkUniversity of Toronto
FundersHealth CanadaKnut och Alice Wallenbergs StiftelseVetenskapsrådetGovernment of CanadaCanadian Blood ServicesAustralian Government
KeywordsHemolysisABO blood group systemZygosityMedicineAntibodyImmunologyInternal medicineGastroenterologyBiologyGenetics

Abstract

fetched live from OpenAlex

TO THE EDITOR: Although frequently effective[1][1],[2][2] and usually benign, high-dose (2 g/kg) intravenous immunoglobulin (IVIG) therapy can result in marked red blood cell (RBC) hemolysis, which in some cases is life threatening in severity.[3][3][⇓][4]-[5][5] The mechanism by which this

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.593
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.258
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations22
Published2018
Admission routes2
Has abstractyes

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