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Record W2784034011 · doi:10.1002/ecs2.2055

Use of environmental sites by mule deer: a proxy for relative risk of chronic wasting disease exposure and transmission

2018· article· en· W2784034011 on OpenAlexafffundabout
María Fernanda Mejía‐Salazar, Cheryl Waldner, Yeen Ten Hwang, Trent K. Bollinger

Bibliographic record

VenueEcosphere · 2018
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPrion Diseases and Protein Misfolding
Canadian institutionsGovernment of SaskatchewanCanadian Bulletin of Medical HistoryMinistry of EnvironmentSaskatchewan Ministry of AgricultureUniversity of Saskatchewan
FundersConsejo Nacional de Ciencia y TecnologíaMinistry of Environment - SaskatchewanMinistry of EnvironmentCanadian Wildlife FederationCanadian Wildlife Health CooperativeUniversity of Saskatchewan
KeywordsChronic wasting diseaseOdocoileusBiologyWildlifeTransmission (telecommunications)EcologyVeterinary medicineDiseaseEnvironmental healthMedicinePrion proteinPathology

Abstract

fetched live from OpenAlex

Abstract Prions that cause chronic wasting disease ( CWD ) in cervids can remain infective for years outside the host. Infectious cervids shed prions for a long time, consequently depositing prions in frequently used areas. These environmental prions are important in CWD epidemiology. Unfortunately, effective tools for quantifying CWD prions in soil, water, and other environmental sources are not currently available. Our goal was to investigate relative differences in visits by mule deer ( Odocoileus hemionus hemionus ) to various environmental site types as an indicator of the relative risk of prion contamination and disease transmission. For this, we deployed a system of triggered‐by‐movement cameras at eight site types in a CWD ‐endemic area in Saskatchewan, Canada. We first assessed whether the relative differences among site types in the frequency of visits by mule deer of any sex‐and‐age class, males, and females varied by season and site type. We then assessed whether the rate of behaviors with a high risk of environmental prion transmission (either contamination or acquisition) differed by season and site type. Finally, we assessed whether the intensity of visitation, based on the number of animals per picture, differed by season and site type. We found that grain sources and beds were key attractants for mule deer: (1) The greatest number of pictures with mule deer per camera‐day occurred at grain sources across all seasons, except in fawning, when beds were the most visited sites; (2) during pre‐rut and early gestation, mule deer visited grain sources at least twice as often as most other sites; (3) females were more likely to visit beds and grain sources, but there was no significant site preferences for males after accounting for season; (4) mule deer were most likely to be pictured contacting the environment at grain sources in early gestation; and (5) beds and grain sources were the most intensively visited sites. We also found that environmental contacts at waterholes were more frequent during spring. We discuss the potential importance of various sites in the transmission of CWD and how their modification could potentially reduce the risk of prion environmental exposure among mule deer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.055
Threshold uncertainty score0.317

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.216
Teacher spread0.209 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2018
Admission routes3
Has abstractyes

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