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Record W2790758123 · doi:10.1002/gch2.201700071

Chiral MoS<sub>2</sub> Quantum Dots: Dual‐Mode Detection Approaches for Avian Influenza Viruses

2018· article· en· W2790758123 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueGlobal Challenges · 2018
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced biosensing and bioanalysis techniques
Canadian institutionsUniversity of Guelph
FundersNatural Sciences and Engineering Research Council of CanadaUniversity of Guelph
KeywordsQuantum dotMaterials scienceConjugated systemChirality (physics)Molybdenum disulfideFluorescenceNanoparticleNanotechnologyPolymerOptics

Abstract

fetched live from OpenAlex

Abstract Molybdenum disulfide (MoS 2 ), a type of transition metal dichalcogenide material, has emerged as an important class among 2D systems. When 2D MoS 2 materials are reduced to 0D quantum dots (QDs), they introduce new optical properties that point to several potential technological advantages in electronic, magnetic, optical, and catalytic properties. In this study, a simple way to produce chiral MoS 2 QDs from MoS 2 nanopowder is presented using l (+)‐ascorbic acid as a reducing agent. The calculated quantum yield of QDs is 11.06%. Experimental results reveal that the size of QDs is uniformly monodispersed (2–3 nm) and have a blue emissive fluorescence peak and circular dichroism (CD) peak located at 420 and 330 nm, respectively. Furthermore, a dual‐mode detection system based on fluorescence and chirality is performed using as‐synthesized MoS 2 QDs, where QDs are conjugated with anti‐hemagglutinin antibodies of avian influenza virus and made into an immunobridge in the presence of target virus and anti‐neuraminidase antibodies conjugated magnetic nanoparticles (MNPs). The photoluminescence and CD spectra of unconjugated QDs after separated magnetochirofluorescent (MNPs‐QDs) nanohybrids by external magnets enables influenza virus A (H5N1) detection with the limit of detection value of 7.35 and 80.92 pg mL −1 , respectively.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.157
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.313
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it