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Record W2792309348 · doi:10.17352/ojps.000005

Effect of a twin-herb formula for the Treatment of Chronic Non-healing Ulcers: a Clinical Study

2017· article· en· W2792309348 on OpenAlexaff
LUK Nai-Ming, KO Chun-Hay, Hung Leung Kim

Bibliographic record

VenueOpen Journal of Plant Science · 2017
Typearticle
Languageen
FieldMedicine
TopicWound Healing and Treatments
Canadian institutionsGuenther Dermatology Research Centre
FundersState Key Laboratory of Phytochemistry and Plant Resources in West ChinaChinese University of Hong Kong
KeywordsMedicineRefractory (planetary science)SurgeryClinical trialWound healingInternal medicineBiology

Abstract

fetched live from OpenAlex

Forty-four patients (27 males and 17 females) with Chronic Non-healing Ulcers that had been refractory to conventional treatment were enrolled in a single arm pre-and post-treatment clinical trial.A twin-herb formula was provided for the treatment for the 6-month study period.All conventional treatment of wound care remained unchanged.Their ulcers were assessed every month.The ulcer sizes greatest length and width was measured at baseline.The target ulcer was assessed at baseline and then every month for 6 months or healed.The mean age of patients was 66.6 (38.0-93.0)years.The mean surface area of ulcers was 28.0±77.1 cm 2 and 14.8±55.0cm 2 at baseline and six months of study respectively.Differences in ulcer area between the initial and fi nal visit were signifi cant (p<0.001).The mean healing time was 149 days (median 167 days).Our results showed that the two-herb recipe (NF3) could reduce the wound size about 50% during 6 months period.36.7% ulcers were healed.No adverse side effects were founded in our patients during study period.The twin-herb formula showed promising results in initiating the healing process in chronic nonhealing ulcers.It was found to be well tolerated and safe to use.However, further clinical trials should be performed involving a control group to verify these data.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.095
GPT teacher head0.485
Teacher spread0.390 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

Explore more

Same venueOpen Journal of Plant Science→Same topicWound Healing and Treatments→French-language works237,207→