AB088. Quality of life and visual function in patients with Boston type I keratoprosthesis
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Background: To determine patient-reported vision-related quality of life (VR-QoL) following Boston type I keratoprosthesis (BI-KPro) surgery and its association with postoperative best-corrected visual acuity (BCVA). Methods: Descriptive cross-sectional study. Consecutive consenting patients with BI-KPro were included. The French National Eye Institute Visual Function Questionnaire-25 administered at 51±18 months postoperatively measured VR-QoL. Clinical charts were reviewed for demographics, indications for BI-KPro, baseline and postoperative (at time of interview) BCVA. For patients operated unilaterally, stratification of VR-QoL scores based on BCVA in the non-operated eye was performed. Multivariate linear regression was carried out, using VR-QoL scores as dependent variables, and demographics and postoperative BCVA as covariates. For patients operated bilaterally, Spearman correlation between VR-QoL scores and BCVA was performed. P<0.05 indicated statistical significance. Results: Sixty-four patients, aged 59±14 years, 52% male, with a follow-up of 54±19 months, were included. Postoperative BCVA increased from baseline in all operated eyes (P=0.000). In patients with unilateral BI-KPro (n=52), the VR-QoL overall score was 70.7±25.1. Scores on all questionnaire subscales were greater when BCVA in the non-operated eye was >20/200 compared to 20/200 (P=0.000). BCVA in the non-operated eye was positively associated with all subscales (P<0.01) independently of age, sex, follow-up duration and postoperative BCVA in the operated eye. In patients with bilateral BI-KPro (n=12) the VR-QoL overall score was 63.0±18.7. BCVA in the best eye positively correlated with Near/Distance activities, and social functioning subscales (P<0.05). There was no significant difference between VR-QoL scores of patients operated unilaterally vs. bilaterally. Conclusions: We describe VR-QoL more than 4 years after BI-KPro surgery. Compared to data at 1 year previously reported, our results suggest that, as vision progressively deteriorates in the operated eye, patients increasingly rely on their non-operated eye. VR-QoL after bilateral BI-KPro is assessed for the first time, and appears comparable to that after unilateral surgery. Larger, prospective, long-term studies, with assessment at baseline, are warranted.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it