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Record W2797882406 · doi:10.1136/jramc-2018-000956

Guidelines for using animal models in blast injury research

2018· article· en· W2797882406 on OpenAlexaff
Sarah Watts, Emrys Kirkman, Dan Bieler, Stephen Bjarnason, Axel Franke, Rishi Gupta, Michael J. Leggieri, Hans Orru, Simon Ouellet, M.M.G.M. Philippens, J-C Sarron, Stian Skriudalen, Jan Arild Teland, Mårten Risling, Ibolja Černak

Bibliographic record

VenueJournal of the Royal Army Medical Corps · 2018
Typearticle
Languageen
FieldHealth Professions
TopicDisaster Response and Management
Canadian institutionsDefence Research and Development Canada
Fundersnot available
KeywordsBlast injuryAnimal modelTask (project management)Set (abstract data type)MedicineComputer sciencePoison controlMedical emergencyEngineeringSystems engineering

Abstract

fetched live from OpenAlex

Blast injury is a very complex phenomenon and frequently results in multiple injuries. One method to investigate the consequences of blast injuries is with the use of living systems (animal models). The use of animals allows the examination and evaluation of injury mechanisms in a more controlled manner, allowing variables such as primary or secondary blast injury for example, to be isolated and manipulated as required. To ensure a degree of standardisation across the blast research community a set of guidelines which helps researchers navigate challenges of modelling blast injuries in animals is required. This paper describes the guidelines for Using Animal Models in Blast Injury Research developed by the NATO Health Factors and Medicine (HFM) Research Task Group 234.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.082
metaresearch head score (Gemma)0.051
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.082
Threshold uncertainty score0.431

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0820.051
Meta-epidemiology (narrow)0.0030.003
Meta-epidemiology (broad)0.0040.004
Bibliometrics0.0080.005
Science and technology studies0.0040.006
Scholarly communication0.0060.003
Open science0.0140.004
Research integrity0.0140.011
Insufficient payload (model declined to judge)0.0120.016

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.473
GPT teacher head0.581
Teacher spread0.108 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations20
Published2018
Admission routes1
Has abstractyes

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